Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 2.312


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GABPAchr21_+_27107522-0.523.1e-03Click!
GABPB1chr15_-_506473490.393.5e-02Click!
ELK4chr1_-_2056019990.355.9e-02Click!
ELK1chrX_-_475099930.106.0e-01Click!


Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_80574853 10.910 NM_130897
DYNLRB2
dynein, light chain, roadblock-type 2
chr15_+_71184781 6.158 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr1_-_67390413 5.858 NM_024763
NM_207014
WDR78

WD repeat domain 78

chr17_+_45908992 5.470 NM_033413
LRRC46
leucine rich repeat containing 46
chr11_-_47736896 4.856 NM_024783
AGBL2
ATP/GTP binding protein-like 2
chr11_-_111944757 4.842 NM_001082619
NM_138789
PIH1D2

PIH1 domain containing 2

chr11_+_61129831 4.790 TMEM138
transmembrane protein 138
chr3_-_47324255 4.463 NM_001134878
NM_022342
NM_182902
KIF9


kinesin family member 9


chr11_+_6502607 4.389 NM_012192
FXC1
fracture callus 1 homolog (rat)
chr21_-_33984865 4.288 NM_021254
C21orf59
chromosome 21 open reading frame 59
chr1_+_118472364 4.197 NM_006784
WDR3
WD repeat domain 3
chr20_+_49575347 3.956 NM_014484
MOCS3
molybdenum cofactor synthesis 3
chr3_-_180397261 3.819 NM_181426
CCDC39
coiled-coil domain containing 39
chr1_+_20512577 3.783 NM_152376
UBXN10
UBX domain protein 10
chr11_+_61129407 3.779 NM_016464
TMEM138
transmembrane protein 138
chr2_-_27603584 3.747 NM_144631
ZNF513
zinc finger protein 513
chr2_+_219536719 3.706 NM_001243313
NM_015690
STK36

serine/threonine kinase 36

chr2_-_99771186 3.620 NM_025244
TSGA10
testis specific, 10
chr2_-_27603249 3.602 NM_001201459
ZNF513
zinc finger protein 513
chrX_-_99665270 3.585 NM_001105243
NM_001184880
NM_020766
PCDH19


protocadherin 19


chr2_-_239148545 3.558 HES6
hairy and enhancer of split 6 (Drosophila)
chr10_-_53459309 3.459 NM_015235
CSTF2T
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr9_-_100395553 3.456 TSTD2
thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr7_+_102105459 3.445 LRWD1
leucine-rich repeats and WD repeat domain containing 1
chr9_-_35749209 3.410 NM_020944
GBA2
glucosidase, beta (bile acid) 2
chr5_-_180018465 3.410 NM_052863
SCGB3A1
secretoglobin, family 3A, member 1
chr16_+_2880172 3.345 NM_145252
ZG16B
zymogen granule protein 16 homolog B (rat)
chr9_-_35749144 3.337 GBA2
glucosidase, beta (bile acid) 2
chr2_-_220110116 3.329 NM_024506
GLB1L
galactosidase, beta 1-like
chr3_-_93781659 3.328 NM_176815
DHFRL1
dihydrofolate reductase-like 1
chr2_-_239148626 3.318 NM_001142853
NM_018645
HES6

hairy and enhancer of split 6 (Drosophila)

chr3_-_127842566 3.254 NM_003707
RUVBL1
RuvB-like 1 (E. coli)
chr20_+_56725982 3.183 NM_178456
C20orf85
chromosome 20 open reading frame 85
chr21_-_33984657 3.170 C21orf59
chromosome 21 open reading frame 59
chr17_-_19281494 3.152 NM_001243475
B9D1
B9 protein domain 1
chrY_+_2709596 3.145 NM_001008
RPS4Y1
ribosomal protein S4, Y-linked 1
chrY_+_2709630 3.117 RPS4Y1
ribosomal protein S4, Y-linked 1
chr1_-_169336999 3.031 NM_013330
NM_197972
NME7

non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)

chr9_-_100395961 3.014 NM_139246
TSTD2
thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr19_-_12807394 2.989 NM_032301
FBXW9
F-box and WD repeat domain containing 9
chr9_+_131218402 2.959 ODF2
outer dense fiber of sperm tails 2
chr9_+_131218426 2.920 ODF2
outer dense fiber of sperm tails 2
chr1_-_160001529 2.907 PIGM
phosphatidylinositol glycan anchor biosynthesis, class M
chr3_-_142297565 2.885 ATR
ataxia telangiectasia and Rad3 related
chr17_+_7487125 2.869 MPDU1
mannose-P-dolichol utilization defect 1
chr14_+_100842728 2.829 NM_001161476
NM_024515
WDR25

WD repeat domain 25

chr1_-_47779651 2.819 NM_001048166
NM_003035
STIL

SCL/TAL1 interrupting locus

chr10_+_22634373 2.813 NM_001253854
NM_001253855
NM_012443
NM_172242
SPAG6



sperm associated antigen 6



chr3_+_32726659 2.812 NM_015442
CNOT10
CCR4-NOT transcription complex, subunit 10
chr5_-_35938736 2.800 NM_001042625
NM_144647
CAPSL

calcyphosine-like

chr11_+_61159818 2.783 NM_001173990
NM_001173991
NM_016499
TMEM216


transmembrane protein 216


chr19_-_55791490 2.780 HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr9_+_131218678 2.770 NM_153433
NM_153440
ODF2

outer dense fiber of sperm tails 2

chr9_+_35732629 2.748 CREB3
cAMP responsive element binding protein 3
chr9_-_35748875 2.698 GBA2
glucosidase, beta (bile acid) 2
chr3_-_194392938 2.663 LSG1
large subunit GTPase 1 homolog (S. cerevisiae)
chr11_+_61197574 2.633 NM_017841
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr9_+_131218435 2.574 ODF2
outer dense fiber of sperm tails 2
chr19_+_32896515 2.573 NM_001172774
DPY19L3
dpy-19-like 3 (C. elegans)
chr3_-_129118241 2.565 RPL32P3
ribosomal protein L32 pseudogene 3
chr16_+_57769667 2.552 KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr17_+_4981754 2.532 ZFP3
zinc finger protein 3 homolog (mouse)
chr14_+_105953531 2.531 CRIP1
cysteine-rich protein 1 (intestinal)
chr11_+_61160098 2.523 TMEM216
transmembrane protein 216
chr3_-_142297650 2.519 NM_001184
ATR
ataxia telangiectasia and Rad3 related
chr19_-_55791446 2.500 HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr12_-_105629790 2.500 NM_001251904
NM_018171
APPL2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr7_+_39605871 2.496 NM_020192
YAE1D1
Yae1 domain containing 1
chr3_-_93782066 2.494 NM_001195643
DHFRL1
dihydrofolate reductase-like 1
chr11_-_6502563 2.493 NM_001242854
NM_001242855
NM_001242856
NM_012402
ARFIP2



ADP-ribosylation factor interacting protein 2



chr6_+_7390012 2.482 NM_031480
RIOK1
RIO kinase 1 (yeast)
chr11_-_6502524 2.479 ARFIP2
ADP-ribosylation factor interacting protein 2
chr6_+_33422319 2.468 NM_152735
ZBTB9
zinc finger and BTB domain containing 9
chr11_+_71791376 2.467 NM_001145307
NM_001145308
NM_001205138
NM_145309
LRTOMT



leucine rich transmembrane and 0-methyltransferase domain containing



chr16_+_89724175 2.451 NM_153025
C16orf55
chromosome 16 open reading frame 55
chr9_+_131218279 2.444 NM_001242352
NM_001242353
NM_001242354
NM_002540
NM_153432
NM_153435
NM_153439
ODF2






outer dense fiber of sperm tails 2






chr17_-_74137370 2.398 NM_001454
FOXJ1
forkhead box J1
chr7_+_48075107 2.387 NM_001100159
C7orf57
chromosome 7 open reading frame 57
chr16_-_54319966 2.369 IRX3
iroquois homeobox 3
chr19_-_44860798 2.365 NM_001083335
NM_013380
ZFP112

zinc finger protein 112 homolog (mouse)

chr19_-_55791428 2.362 HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr19_-_55791727 2.361 NM_001130106
NM_012267
HSPBP1

HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1

chr12_+_124118312 2.350 NM_001516
GTF2H3
general transcription factor IIH, polypeptide 3, 34kDa
chr15_+_44092782 2.331 C15orf63
chromosome 15 open reading frame 63
chr1_+_22351984 2.309 LINC00339
long intergenic non-protein coding RNA 339
chr2_+_172378856 2.304 NM_001127383
NM_024843
CYBRD1

cytochrome b reductase 1

chr19_-_19774472 2.303 ATP13A1
ATPase type 13A1
chr7_+_102987970 2.261 NM_001204453
NM_002803
PSMC2

proteasome (prosome, macropain) 26S subunit, ATPase, 2

chr15_+_44092618 2.239 NM_001199885
NM_016400
C15orf63

chromosome 15 open reading frame 63

chr1_+_44679111 2.231 NM_001034023
NM_001034024
NM_019100
DMAP1


DNA methyltransferase 1 associated protein 1


chr3_-_194392881 2.205 LSG1
large subunit GTPase 1 homolog (S. cerevisiae)
chr2_+_27805892 2.191 NM_032434
ZNF512
zinc finger protein 512
chr19_-_48825150 2.183 CCDC114
coiled-coil domain containing 114
chrY_-_2368579 2.173 NM_001171135
ZBED1
zinc finger, BED-type containing 1
chr13_-_29292961 2.172 NM_001135919
NM_181785
SLC46A3

solute carrier family 46, member 3

chr21_-_46340776 2.162 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr11_+_35684418 2.139 TRIM44
tripartite motif containing 44
chr19_-_19774501 2.129 NM_020410
ATP13A1
ATPase type 13A1
chr2_-_28113211 2.103 NM_022128
RBKS
ribokinase
chr14_+_77924367 2.097 NM_012111
AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr1_+_46049659 2.095 NM_001195193
NM_002482
NM_152298
NASP


nuclear autoantigenic sperm protein (histone-binding)


chr19_+_44645728 2.085 ZNF234
zinc finger protein 234
chr6_+_18155535 2.071 NM_153042
KDM1B
lysine (K)-specific demethylase 1B
chr21_-_46340821 2.067 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr17_-_3867585 2.066 NM_005173
NM_174953
NM_174954
NM_174955
NM_174956
NM_174957
NM_174958
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr17_+_34891340 2.063 NM_178517
PIGW
phosphatidylinositol glycan anchor biosynthesis, class W
chr12_-_25348031 2.060 NM_001082972
NM_001082973
NM_001204101
NM_001204102
NM_018272
CASC1




cancer susceptibility candidate 1




chr2_-_73964427 2.050 NM_016058
TPRKB
TP53RK binding protein
chr17_+_4981721 2.030 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chr14_+_77924415 2.030 AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr12_+_498513 2.024 NM_001130147
NM_001130148
CCDC77

coiled-coil domain containing 77

chr9_+_35732498 2.018 CREB3
cAMP responsive element binding protein 3
chr10_+_99894426 2.010 C10orf28
chromosome 10 open reading frame 28
chr6_+_32811895 2.001


chr2_+_201754049 1.998 NM_001136039
NM_001142355
NM_021824
NIF3L1


NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)


chr1_-_160001723 1.997 NM_145167
PIGM
phosphatidylinositol glycan anchor biosynthesis, class M
chr15_-_85197512 1.994 NM_032856
WDR73
WD repeat domain 73
chrX_+_55478537 1.990 NM_014061
MAGEH1
melanoma antigen family H, 1
chr1_+_217804665 1.968 NM_138796
SPATA17
spermatogenesis associated 17
chr1_-_109969058 1.967 NM_001199772
NM_002790
NM_001199773
NM_001199774
PSMA5



proteasome (prosome, macropain) subunit, alpha type, 5



chr11_-_95522685 1.961 FAM76B
family with sequence similarity 76, member B
chr14_-_54423448 1.960 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chr17_+_79935493 1.957 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr2_-_99758034 1.956 NM_182911
TSGA10
testis specific, 10
chr19_+_36236460 1.955 NM_172341
PSENEN
presenilin enhancer 2 homolog (C. elegans)
chr19_+_58816757 1.955 ERVK3-1
endogenous retrovirus group K3, member 1
chrX_+_47092362 1.953 USP11
ubiquitin specific peptidase 11
chr3_-_72897575 1.951 SHQ1
SHQ1 homolog (S. cerevisiae)
chr9_+_35732207 1.950 NM_006368
CREB3
cAMP responsive element binding protein 3
chr3_-_51533906 1.932 VPRBP
Vpr (HIV-1) binding protein
chr16_+_699277 1.919 NM_145294
WDR90
WD repeat domain 90
chr20_+_48429375 1.913 SLC9A8
solute carrier family 9 (sodium/hydrogen exchanger), member 8
chr22_+_46067677 1.912 NM_001167621
NM_013236
ATXN10

ataxin 10

chr15_-_85197502 1.910 WDR73
WD repeat domain 73
chr9_+_34458810 1.910 NM_012144
DNAI1
dynein, axonemal, intermediate chain 1
chr5_-_68485278 1.906


chr1_+_246729724 1.906 CNST
consortin, connexin sorting protein
chr11_-_64885124 1.903 NM_014205
ZNHIT2
zinc finger, HIT-type containing 2
chr16_+_89724436 1.902 C16orf55
chromosome 16 open reading frame 55
chr9_-_3525973 1.900 NM_002919
NM_134428
RFX3

regulatory factor X, 3 (influences HLA class II expression)

chr3_-_194392913 1.899 LSG1
large subunit GTPase 1 homolog (S. cerevisiae)
chr9_+_100395704 1.891 NM_002486
NCBP1
nuclear cap binding protein subunit 1, 80kDa
chr17_+_40985444 1.885 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr2_-_99224868 1.882 NM_001008215
COA5
cytochrome C oxidase assembly factor 5
chr21_-_46340874 1.865 NM_000211
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr2_+_85980600 1.865 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr8_+_67341244 1.863 NM_015169
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr3_-_183273407 1.862 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr1_+_246729803 1.861 CNST
consortin, connexin sorting protein
chrY_-_2368963 1.850 NM_145177
NM_001171136
NM_004729
DHRSX
ZBED1

dehydrogenase/reductase (SDR family) X-linked
zinc finger, BED-type containing 1

chr1_-_38273823 1.849 YRDC
yrdC domain containing (E. coli)
chr12_+_74931622 1.842 ATXN7L3B
ataxin 7-like 3B
chr17_-_7218665 1.840 GPS2
G protein pathway suppressor 2
chr2_+_99225084 1.826 UNC50
unc-50 homolog (C. elegans)
chr1_+_161123755 1.825 UFC1
ubiquitin-fold modifier conjugating enzyme 1
chr15_-_89089792 1.825 NM_001144074
NM_017996
DET1

de-etiolated homolog 1 (Arabidopsis)

chr17_+_7486964 1.825 NM_004870
MPDU1
mannose-P-dolichol utilization defect 1
chr12_+_124196941 1.818 ATP6V0A2
ATPase, H+ transporting, lysosomal V0 subunit a2
chr16_+_67226027 1.815 NM_001950
E2F4
E2F transcription factor 4, p107/p130-binding
chr1_-_42921923 1.815 NM_001146192
NM_032257
ZMYND12

zinc finger, MYND-type containing 12

chr13_-_31736031 1.814 NM_006644
HSPH1
heat shock 105kDa/110kDa protein 1
chr12_+_74931550 1.812 NM_001136262
ATXN7L3B
ataxin 7-like 3B
chrX_+_47092264 1.812 NM_004651
USP11
ubiquitin specific peptidase 11
chr17_-_7218370 1.805 NM_004489
GPS2
G protein pathway suppressor 2
chr14_+_45431333 1.800 NM_015091
FAM179B
family with sequence similarity 179, member B
chr9_-_117150217 1.795 AKNA
AT-hook transcription factor
chr3_-_194393205 1.789 NM_018385
LSG1
large subunit GTPase 1 homolog (S. cerevisiae)
chr15_+_82555101 1.789 NM_001008226
FAM154B
family with sequence similarity 154, member B
chr11_-_22647329 1.788 NM_022725
FANCF
Fanconi anemia, complementation group F
chr2_-_70418086 1.784 NM_017880
C2orf42
chromosome 2 open reading frame 42
chr22_+_46067892 1.775 ATXN10
ataxin 10
chr16_-_58163181 1.772 C16orf80
chromosome 16 open reading frame 80
chr16_+_4784261 1.772 NM_139170
C16orf71
chromosome 16 open reading frame 71
chr11_+_65479685 1.771 KAT5
K(lysine) acetyltransferase 5
chrX_+_129473812 1.770 NM_003951
NM_022810
SLC25A14

solute carrier family 25 (mitochondrial carrier, brain), member 14

chr4_-_159644439 1.766 NM_005038
PPID
peptidylprolyl isomerase D
chr2_+_99225060 1.756 UNC50
unc-50 homolog (C. elegans)
chr4_+_980775 1.748 NM_000203
IDUA
iduronidase, alpha-L-
chr20_+_62612464 1.745 PRPF6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)
chr11_+_2421983 1.741 TSSC4
tumor suppressing subtransferable candidate 4
chr2_+_32390902 1.731 NM_001193513
NM_001193514
NM_001193515
NM_017964
SLC30A6



solute carrier family 30 (zinc transporter), member 6



chr8_+_144329105 1.727 NM_173832
ZFP41
zinc finger protein 41 homolog (mouse)
chr11_-_95522640 1.724 FAM76B
family with sequence similarity 76, member B
chr19_-_45681454 1.720 NM_024108
TRAPPC6A
trafficking protein particle complex 6A
chr8_-_104427319 1.716 SLC25A32
solute carrier family 25, member 32
chr6_-_36842751 1.716 PPIL1
peptidylprolyl isomerase (cyclophilin)-like 1
chr10_-_98480174 1.713 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr10_+_99894380 1.705 NM_014472
C10orf28
chromosome 10 open reading frame 28
chrX_+_150565655 1.705 NM_001017980
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr2_-_241500167 1.701 ANKMY1
ankyrin repeat and MYND domain containing 1
chr5_-_130970803 1.694 RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr11_-_124670283 1.693 NM_024631
C11orf61
chromosome 11 open reading frame 61
chr20_-_44993000 1.687 NM_015945
NM_173073
NM_173179
SLC35C2


solute carrier family 35, member C2


chr8_-_143751322 1.682 JRK
jerky homolog (mouse)
chr17_+_40985416 1.680 NM_005789
NM_176863
PSME3

proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)

chr11_+_48002063 1.678 NM_001098503
NM_002843
PTPRJ

protein tyrosine phosphatase, receptor type, J

chr2_+_99225041 1.676 NM_014044
UNC50
unc-50 homolog (C. elegans)
chr16_-_58163286 1.675 NM_013242
C16orf80
chromosome 16 open reading frame 80
chr19_+_8455243 1.672 RAB11B
RAB11B, member RAS oncogene family
chr6_-_36842547 1.664 PPIL1
peptidylprolyl isomerase (cyclophilin)-like 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.36 3.41e-35 GO:0044260 cellular macromolecule metabolic process
1.52 2.49e-30 GO:0090304 nucleic acid metabolic process
1.29 2.91e-27 GO:0043170 macromolecule metabolic process
1.43 3.04e-27 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56 6.13e-26 GO:0016070 RNA metabolic process
1.22 9.89e-22 GO:0044237 cellular metabolic process
1.97 2.40e-21 GO:0016071 mRNA metabolic process
1.87 5.95e-21 GO:0006396 RNA processing
1.47 7.14e-20 GO:0010467 gene expression
1.33 3.57e-18 GO:0034641 cellular nitrogen compound metabolic process
1.31 1.89e-16 GO:0006807 nitrogen compound metabolic process
1.97 6.45e-15 GO:0006397 mRNA processing
1.17 8.28e-15 GO:0008152 metabolic process
2.08 2.31e-14 GO:0008380 RNA splicing
2.29 1.54e-13 GO:0000375 RNA splicing, via transesterification reactions
1.17 4.92e-13 GO:0044238 primary metabolic process
2.28 8.32e-13 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.28 8.32e-13 GO:0000398 nuclear mRNA splicing, via spliceosome
1.39 1.58e-11 GO:0009059 macromolecule biosynthetic process
1.58 3.06e-11 GO:0046907 intracellular transport
1.39 3.41e-11 GO:0034645 cellular macromolecule biosynthetic process
1.30 1.08e-10 GO:0044267 cellular protein metabolic process
1.28 4.46e-10 GO:0071841 cellular component organization or biogenesis at cellular level
1.69 9.12e-10 GO:0006974 response to DNA damage stimulus
1.52 1.92e-09 GO:0033554 cellular response to stress
2.06 2.13e-08 GO:0022613 ribonucleoprotein complex biogenesis
1.23 2.21e-08 GO:0060255 regulation of macromolecule metabolic process
2.03 2.39e-08 GO:0071843 cellular component biogenesis at cellular level
1.22 4.79e-08 GO:0071840 cellular component organization or biogenesis
1.75 5.63e-08 GO:0016568 chromatin modification
1.57 1.83e-07 GO:0006259 DNA metabolic process
1.68 3.35e-07 GO:0016032 viral reproduction
1.44 1.44e-06 GO:0006351 transcription, DNA-dependent
1.24 1.63e-06 GO:0071842 cellular component organization at cellular level
1.24 1.81e-06 GO:0010468 regulation of gene expression
2.57 1.83e-06 GO:0006353 transcription termination, DNA-dependent
1.96 2.15e-06 GO:0034470 ncRNA processing
1.24 3.02e-06 GO:0044249 cellular biosynthetic process
1.07 8.00e-06 GO:0009987 cellular process
1.18 8.02e-06 GO:0019222 regulation of metabolic process
1.39 8.28e-06 GO:0032774 RNA biosynthetic process
1.42 8.54e-06 GO:0015031 protein transport
1.19 8.97e-06 GO:0031323 regulation of cellular metabolic process
1.30 1.04e-05 GO:0006996 organelle organization
1.42 1.10e-05 GO:0045184 establishment of protein localization
1.27 1.15e-05 GO:0043412 macromolecule modification
1.23 1.18e-05 GO:0009058 biosynthetic process
1.75 1.74e-05 GO:0034660 ncRNA metabolic process
1.48 3.59e-05 GO:0051276 chromosome organization
1.20 4.61e-05 GO:0019538 protein metabolic process
1.48 4.78e-05 GO:0009057 macromolecule catabolic process
1.18 4.82e-05 GO:0080090 regulation of primary metabolic process
1.18 5.32e-05 GO:0016043 cellular component organization
1.64 5.44e-05 GO:0006281 DNA repair
1.36 5.46e-05 GO:0007049 cell cycle
1.34 6.84e-05 GO:0051649 establishment of localization in cell
1.23 6.96e-05 GO:0051252 regulation of RNA metabolic process
1.51 9.14e-05 GO:0044265 cellular macromolecule catabolic process
1.26 9.77e-05 GO:0006464 protein modification process
1.20 1.06e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.21 1.32e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.34 1.78e-04 GO:0008104 protein localization
1.21 2.19e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.59 2.38e-04 GO:0030163 protein catabolic process
1.77 3.07e-04 GO:0000075 cell cycle checkpoint
1.30 3.11e-04 GO:0051641 cellular localization
2.31 3.20e-04 GO:0006354 transcription elongation, DNA-dependent
1.62 3.25e-04 GO:0051603 proteolysis involved in cellular protein catabolic process
1.75 3.84e-04 GO:0071156 regulation of cell cycle arrest
1.64 4.30e-04 GO:0051329 interphase of mitotic cell cycle
1.60 4.70e-04 GO:0070647 protein modification by small protein conjugation or removal
2.00 5.05e-04 GO:0042254 ribosome biogenesis
1.63 5.54e-04 GO:0051325 interphase
1.43 6.15e-04 GO:0051726 regulation of cell cycle
2.17 6.74e-04 GO:0006352 transcription initiation, DNA-dependent
1.61 7.49e-04 GO:0006511 ubiquitin-dependent protein catabolic process
1.45 8.50e-04 GO:0000278 mitotic cell cycle
1.50 9.28e-04 GO:0006325 chromatin organization
1.58 9.61e-04 GO:0044257 cellular protein catabolic process
1.57 1.05e-03 GO:0010564 regulation of cell cycle process
1.19 1.12e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.62 1.12e-03 GO:0006366 transcription from RNA polymerase II promoter
1.60 1.13e-03 GO:0019941 modification-dependent protein catabolic process
1.19 1.47e-03 GO:0031326 regulation of cellular biosynthetic process
1.19 1.52e-03 GO:0009889 regulation of biosynthetic process
1.58 1.62e-03 GO:0043632 modification-dependent macromolecule catabolic process
1.21 1.69e-03 GO:0006355 regulation of transcription, DNA-dependent
2.02 2.13e-03 GO:0000077 DNA damage checkpoint
1.52 2.34e-03 GO:0006886 intracellular protein transport
1.98 2.47e-03 GO:0031570 DNA integrity checkpoint
1.53 4.10e-03 GO:0044419 interspecies interaction between organisms
1.60 5.13e-03 GO:0032446 protein modification by small protein conjugation
1.38 5.38e-03 GO:0022403 cell cycle phase
1.75 5.98e-03 GO:0016569 covalent chromatin modification
1.75 6.75e-03 GO:0016570 histone modification
1.26 8.58e-03 GO:0033036 macromolecule localization
2.05 9.62e-03 GO:0006364 rRNA processing
1.94 1.08e-02 GO:0000084 S phase of mitotic cell cycle
1.33 1.24e-02 GO:0022402 cell cycle process
1.76 1.56e-02 GO:0010498 proteasomal protein catabolic process
1.76 1.56e-02 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.99 1.70e-02 GO:0016072 rRNA metabolic process
1.90 1.92e-02 GO:0051320 S phase
2.17 2.05e-02 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
1.72 2.13e-02 GO:0043687 post-translational protein modification
1.41 2.16e-02 GO:0070727 cellular macromolecule localization
1.58 2.18e-02 GO:0016567 protein ubiquitination
1.41 2.44e-02 GO:0034613 cellular protein localization
2.07 2.50e-02 GO:0000216 M/G1 transition of mitotic cell cycle
2.07 2.50e-02 GO:0051443 positive regulation of ubiquitin-protein ligase activity
1.80 2.84e-02 GO:0007005 mitochondrion organization
2.01 3.00e-02 GO:0002224 toll-like receptor signaling pathway
2.49 3.00e-02 GO:0006369 termination of RNA polymerase II transcription
2.03 3.25e-02 GO:0051351 positive regulation of ligase activity
2.03 3.25e-02 GO:2000045 regulation of G1/S transition of mitotic cell cycle
2.22 3.34e-02 GO:0006368 transcription elongation from RNA polymerase II promoter
2.06 3.76e-02 GO:0008063 Toll signaling pathway
1.98 3.77e-02 GO:0002221 pattern recognition receptor signaling pathway
1.64 4.20e-02 GO:0006457 protein folding
1.26 4.26e-02 GO:0044085 cellular component biogenesis
2.13 4.51e-02 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.13 4.51e-02 GO:0072594 establishment of protein localization to organelle

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.24 1.71e-54 GO:0043227 membrane-bounded organelle
1.24 3.39e-54 GO:0043231 intracellular membrane-bounded organelle
1.16 6.97e-48 GO:0005622 intracellular
1.16 9.96e-48 GO:0044424 intracellular part
1.20 1.04e-45 GO:0043229 intracellular organelle
1.20 2.13e-45 GO:0043226 organelle
1.33 3.29e-43 GO:0005634 nucleus
1.56 7.04e-37 GO:0044428 nuclear part
1.60 9.63e-35 GO:0031981 nuclear lumen
1.51 4.52e-33 GO:0031974 membrane-enclosed lumen
1.52 6.14e-33 GO:0070013 intracellular organelle lumen
1.51 6.73e-32 GO:0043233 organelle lumen
1.60 1.17e-23 GO:0005654 nucleoplasm
1.24 1.82e-23 GO:0044446 intracellular organelle part
1.24 1.35e-22 GO:0044422 organelle part
1.70 1.76e-16 GO:0044451 nucleoplasm part
1.80 4.14e-15 GO:0030529 ribonucleoprotein complex
2.21 1.47e-14 GO:0016604 nuclear body
2.52 2.35e-13 GO:0005681 spliceosomal complex
1.75 5.68e-13 GO:0005730 nucleolus
1.13 4.88e-12 GO:0005737 cytoplasm
1.20 6.98e-08 GO:0032991 macromolecular complex
2.53 2.12e-07 GO:0071013 catalytic step 2 spliceosome
2.18 6.74e-07 GO:0016607 nuclear speck
1.13 1.18e-06 GO:0044444 cytoplasmic part
1.03 4.30e-05 GO:0005623 cell
1.03 5.54e-05 GO:0044464 cell part
2.70 1.45e-04 GO:0015030 Cajal body
1.18 3.29e-04 GO:0043228 non-membrane-bounded organelle
1.18 3.29e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.26 8.49e-04 GO:0005739 mitochondrion
1.37 8.33e-03 GO:0005694 chromosome
1.32 1.32e-02 GO:0031967 organelle envelope
1.97 1.44e-02 GO:0000790 nuclear chromatin
2.85 1.62e-02 GO:0044452 nucleolar part
2.14 1.72e-02 GO:0000123 histone acetyltransferase complex
1.14 2.50e-02 GO:0043234 protein complex
1.30 2.72e-02 GO:0031975 envelope
1.51 3.20e-02 GO:0044440 endosomal part
2.12 3.97e-02 GO:0016605 PML body
1.50 4.23e-02 GO:0010008 endosome membrane
2.04 4.91e-02 GO:0000502 proteasome complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.34 2.80e-23 GO:0003676 nucleic acid binding
1.09 6.15e-15 GO:0005488 binding
1.57 9.41e-13 GO:0003723 RNA binding
1.14 1.61e-11 GO:0005515 protein binding
1.28 1.07e-09 GO:0003677 DNA binding
1.28 6.62e-08 GO:0008270 zinc ion binding
1.23 9.10e-06 GO:0046914 transition metal ion binding
1.90 2.44e-05 GO:0008168 methyltransferase activity
1.98 4.26e-05 GO:0004386 helicase activity
1.85 9.44e-05 GO:0016741 transferase activity, transferring one-carbon groups
2.01 8.28e-04 GO:0008026 ATP-dependent helicase activity
2.01 8.28e-04 GO:0070035 purine NTP-dependent helicase activity
1.51 2.28e-03 GO:0016887 ATPase activity
1.49 2.65e-03 GO:0003712 transcription cofactor activity
1.48 3.07e-03 GO:0000988 protein binding transcription factor activity
1.48 3.07e-03 GO:0000989 transcription factor binding transcription factor activity
1.92 1.63e-02 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
1.52 1.84e-02 GO:0042623 ATPase activity, coupled
1.12 2.46e-02 GO:0043167 ion binding
1.12 2.47e-02 GO:0043169 cation binding
1.16 3.25e-02 GO:0000166 nucleotide binding
1.12 3.62e-02 GO:0046872 metal ion binding